How does hydromorphone compare in potency to oxymorphone?

Hydromorphone is often considered to have slightly less potency compared to oxymorphone. Both are opioids used for pain management, but they differ in their strength. Hydromorphone is approximately five to seven times more potent than morphine, whereas oxymorphone is about three times more potent than morphine. This makes oxymorphone stronger on a milligram per milligram basis, leading to the conclusion that hydromorphone has slightly less potency than oxymorphone. Understanding these nuances in opioid potency is crucial for safe and effective pain management, ensuring that dosages are appropriately adjusted based on the specific medication being used and the patient's needs.