What is a key characteristic of methadone in veterinary medicine?

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Methadone is known for having a lower likelihood of causing vomiting in cats and dogs compared to other opioids. This characteristic makes it especially useful in veterinary medicine, where minimizing side effects like vomiting is crucial for patient comfort and compliance, particularly after surgical procedures or in patients receiving anesthesia. By using methadone, veterinarians can provide effective pain management without the added complication of inducing nausea.

While methadone is indeed a potent analgesic and has a long duration of action, it is not the most potent opioid available; other opioids surpass its potency. It acts on multiple opioid receptors, which broadens its analgesic properties but means it is not exclusively a mu agonist. These attributes highlight methadone’s unique profile in managing pain while reducing adverse effects like vomiting in dogs and cats.

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